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| | ARTICLE | Am. J. innov. res. appl. sci. Volume 12, Issue 4, Pages 109-116 (April, 2021) |
| Research Article |
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| APRIL | VOLUME 12 | N° 4 | 2021 |
| Info-AJIRAS-® Journal ISSN 2429-5396 (Online) / Reference CIF/15/0289M |
American Journal of Innovative Research & Applied Sciences
Authors Contact
*Correspondant author and authors Copyright © 2021:
| Venkataramanaiah Poli 1* | and | Motireddy Srinivasulu Reddy 2 |
Affiliation.
1,2 Department of Zoology | Sri Venkateswara University | Tirupati-517502 A.P | India |
This article is made freely available as part of this journal's Open Access: ID | Poli–Ref1-ajira050421 |
*Corresponding author Author & Copyright Author © 2021: | Venkataramanaiah Poli * |. All Rights Reserved. All articles published in American Journal of Innovative Research and Applied Sciences are the property of Atlantic Center Research Sciences, and is protected by copyright laws CC-BY. See: http://creativecommons.org/licenses/by-nc/4.0/.
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American Journal of innovative
Research & Applied Sciences
Research & Applied Sciences
ISSN 2429-5396 (Online)
OCLC Number: 920041286
OCLC Number: 920041286
ABSTRACT
Background: The purpose of this study is to investigate the antifertility activity of Eugenol (EUG) and Ocimum sanctum (OS) Linn. Leaf extract in female albino rats. Objective: This research was conducted to investigate the effects of Eug and OS in Phytochemistry and evaluate antifertility activities in female rats. Methods: Experiments are carried out to investigate healthy female albino rats given with Eug (99% pure) with a dose of 0.4 ml/day/ rat and OS Linn. (Tulsi) Leaf extract at a dose of 500 mg/kg body weight/day/rat orally for 15 days. Different parameters study in female albino rats, including the estimated hematological and biochemical parameters, observed. Results: Data revealed that the administration of Eugenol and Ocimum sanctum Linn. Extract leaf physicochemical parameters are determined. Phytochemical analysis of plant leaves reveals that the existence of saponins, alkaloids, flavonoids, steroids, phenols, tannins and glycosides. In hematological assessment, the average concentration of WBC, BT, CT, LYS, MON, NEU and PLT significantly (p<0.01) increased in Eug and OS compared to control. Biochemical assessment shows a significant increase (p <0.05) at the Creatinine, Urea, Total Bilirubin and Albumin and Alkaline Phosphates on Eug and OS, compared to control. Conclusions: These results indicate that Eugenol and Ocimum sanctum Linn. Leaf extract must be given carefully because it can cause some infertility levels in female animals.
Key words: Eugenol, Ocimum sanctum , antifertility, phytoconstituents, hematological, biochemical.
Background: The purpose of this study is to investigate the antifertility activity of Eugenol (EUG) and Ocimum sanctum (OS) Linn. Leaf extract in female albino rats. Objective: This research was conducted to investigate the effects of Eug and OS in Phytochemistry and evaluate antifertility activities in female rats. Methods: Experiments are carried out to investigate healthy female albino rats given with Eug (99% pure) with a dose of 0.4 ml/day/ rat and OS Linn. (Tulsi) Leaf extract at a dose of 500 mg/kg body weight/day/rat orally for 15 days. Different parameters study in female albino rats, including the estimated hematological and biochemical parameters, observed. Results: Data revealed that the administration of Eugenol and Ocimum sanctum Linn. Extract leaf physicochemical parameters are determined. Phytochemical analysis of plant leaves reveals that the existence of saponins, alkaloids, flavonoids, steroids, phenols, tannins and glycosides. In hematological assessment, the average concentration of WBC, BT, CT, LYS, MON, NEU and PLT significantly (p<0.01) increased in Eug and OS compared to control. Biochemical assessment shows a significant increase (p <0.05) at the Creatinine, Urea, Total Bilirubin and Albumin and Alkaline Phosphates on Eug and OS, compared to control. Conclusions: These results indicate that Eugenol and Ocimum sanctum Linn. Leaf extract must be given carefully because it can cause some infertility levels in female animals.
Key words: Eugenol, Ocimum sanctum , antifertility, phytoconstituents, hematological, biochemical.
PHYTOCHEMISTRY AND STUDY OF ANTIFERTILITY EFFECTS ON EUGENOL AND OCIMUM SANCTUM LINN. LEAF EXTRACT IN FEMALE RAT
| Venkataramanaiah Poli 1* | and | Motireddy Srinivasulu Reddy 2 |. Am. J. innov. res. appl. sci. 2021; 12(4):109-116
| PDF FULL TEXT | | XML FILE | | Received | April 04, 2021 | | Accepted | April 07, 2021 | | Published | April 12, 2021 |
| Venkataramanaiah Poli 1* | and | Motireddy Srinivasulu Reddy 2 |. Am. J. innov. res. appl. sci. 2021; 12(4):109-116
| PDF FULL TEXT | | XML FILE | | Received | April 04, 2021 | | Accepted | April 07, 2021 | | Published | April 12, 2021 |