| ABSTRACT | Volume 1, Issue 3, Pages 80-84 (May 2015)

Research Article ASSESSMENT OF PLATELET COUNT AND PLATELET INDICES IN PRE-ECLAMPSIA AND ECLAMPSIA. | Biva Rani Mondal | Debatosh Paul | Tuhin Sultana | Quddusur Rahman | Sharmeen Ahmed | Kaniz Fatema | Waqar Ahmed Khan | Bilquis Banu | Mesbah Uddin Ahmed A.N.| and | Nashimuddin Ahmed |. The American Journal of Innovative Research and Applied Sciences. 2015; 1(3):80-84. | PDF FULL TEXT |

ABSTRACT Background: Preeclampsia and eclampsia are major obstetric problem in developing countries like Bangladesh. It remains an important cause of maternal mortality throughout the world. Objective: To compare the platelet count and platelet indices in pre-eclampsia and eclampsia patients with normal pregnancies was aim of this study. Methods: This cross sectional comparative study was conducted in the Department of Clinical Pathology, in collaboration with the department of Obstetrics and Gynecology, BSMMU and department of Obstetrics and Gynecology, Dhaka Medical College Hospital (DMCH) during the period of from March 2012 to February 2013. Patients with 28 weeks’ gestation or more who attended at antenatal care unit or admitted into the Department of Obstetrics and Gynaecology, BSMMU or DMCH, were selected as population of the study. Among them 32 patients with preeclampsia, 32 with eclampsia and 32 normal pregnancies were enrolled in the study as sample by purposive sampling. Blood samples were taken from each patient for platelet count and platelet indices. Platelet count and platelet indices were measured in Haematology auto analyzer (SYSMEX-XT 4000i). Results: Patients of all three groups were matched in terms of age and parity. In the present study the mean platelet counts was 219.69±63.73, 187.50±64.96 and 300.94±69.72 (X109/L) in group I, group II and group III respectively. The mean MPV was 11.55±0.86, 12.16±1.05 and 10.05±0.71 whereas mean platelet distribution width (PDW) was 14.99±2.30, 17.00±2.63 and 11.67±1.58 as well as mean platelet large cell ratio (PLCR) was 36.42±5.90, 40.24±6.69 and 25.33±5.82 in group I, group II and group III respectively. The present study found that the mean platelet volume (MPV), platelet distribution width (PDW)  and PLCR of preeclampsia and eclampsia group was higher than normal group. Conclusion: Platelet count decreases and MPV, PDW and PLCR increases in preeclampsia and eclampsia in comparison to normal pregnancy Key words: Preeclampsia, Eclampsia, Platelet count, Platelet indices